USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: RSSA_HUMAN USC-OGP 2-DE database:  RSSA_HUMAN RSSA_HUMAN General information about the entry View entry in simple text format Entry name RSSA_HUMAN Primary accession number P08865 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803};. Gene name Name=RPSA {ECO:0000255|HAMAP-Rule:MF_03016} Synonyms=LAMBR, LAMR1 Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1227: pI=4.66; Mw=34859 Cross-references UniProtKB/Swiss-Prot P08865; RSSA_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name RSSA_HUMAN Primary accession number P08865 Secondary accession number(s) P11085 P12030 Q16471 Q6IPD1 Q6IPD2 Q6NSD1 Q6NXQ8 Q86VC0 Sequence was last modified on  January 23, 2007 (version 4) Annotations were last modified on  March 15, 2017 (version 195) Name and origin of the protein Description RecName: Full=40S ribosomal protein SA {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37 kDa laminin receptor precursor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=37LRP {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=37/67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LRP/LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=67 kDa laminin receptor {ECO:0000255|HAMAP-Rule:MF_03016}; Short=67LR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Colon carcinoma laminin-binding protein; AltName: Full=Laminin receptor 1 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LamR {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Laminin-binding protein precursor p40 {ECO:0000255|HAMAP-Rule:MF_03016}; Short=LBP/p40 {ECO:0000255|HAMAP-Rule:MF_03016}; AltName: Full=Multidrug resistance-associated protein MGr1-Ag; AltName: Full=NEM/1CHD4; AltName: Full=Small ribosomal subunit protein uS2 {ECO:0000303|PubMed:24524803}; Gene name Name=RPSA {ECO:0000255|HAMAP-Rule:MF_03016} Synonyms=LAMBR, LAMR1 Encoded on Name=RPSA {ECO:0000255|HAMAP-Rule:MF_03016}; Synonyms=LAMBR, LAMR1 Keywords 3D-structure; Acetylation; Cell membrane; Complete proteome; Cytoplasm; Direct protein sequencing; Disease mutation; Host cell receptor for virus entry; Host-virus interaction; Membrane; Nucleus; Phosphoprotein; Polymorphism; Receptor; Reference proteome; Repeat; Ribonucleoprotein; Ribosomal protein. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL J03799; AAA36161.1; -; mRNA EMBL X15005; CAA33112.1; -; mRNA EMBL S37431; AAB22299.1; -; mRNA EMBL U43901; AAC50652.1; -; Genomic_DNA EMBL AF503367; AAM33304.1; -; mRNA EMBL BT007219; AAP35883.1; -; mRNA EMBL BC005391; AAH05391.1; -; mRNA EMBL BC008867; AAH08867.1; -; mRNA EMBL BC010418; AAH10418.1; -; mRNA EMBL BC013827; AAH13827.1; -; mRNA EMBL BC034537; AAH34537.1; -; mRNA EMBL BC050688; AAH50688.1; -; mRNA EMBL BC053370; AAH53370.1; -; mRNA EMBL BC062714; AAH62714.1; -; mRNA EMBL BC066941; AAH66941.1; -; mRNA EMBL BC068062; AAH68062.1; -; mRNA EMBL BC070263; AAH70263.1; -; mRNA EMBL BC071693; AAH71693.1; -; mRNA EMBL BC071968; AAH71968.1; -; mRNA EMBL BC071969; AAH71969.1; -; mRNA EMBL BC071970; AAH71970.1; -; mRNA EMBL BC073863; AAH73863.1; -; mRNA EMBL BC107567; AAI07568.1; -; mRNA EMBL X61156; CAA43469.1; -; mRNA EMBL U36484; AAC50313.1; -; Genomic_DNA EMBL M14199; AAA36165.1; -; mRNA EMBL AB007146; BAA25812.1; -; Genomic_DNA CCDS CCDS2686.1; -; . PIR A31233; A31233; . RefSeq NP_001291217.1; NM_001304288.1; . RefSeq NP_002286.2; NM_002295.5; . UniGene Hs.449909; -; . PDB 3BCH; X-ray; 2.15 A; A=2-220 PDB 4UG0; EM; -; SA=1-295 PDB 4V6X; EM; 5.00 A; AA=1-295 PDB 5A2Q; EM; 3.90 A; A=1-295 PDB 5AJ0; EM; 3.50 A; BA=1-295 PDB 5FLX; EM; 3.90 A; A=1-295 PDB 5T2C; EM; 3.60 A; Ao=1-295 PDBsum 3BCH; -; . PDBsum 4UG0; -; . PDBsum 4V6X; -; . PDBsum 5A2Q; -; . PDBsum 5AJ0; -; . PDBsum 5FLX; -; . PDBsum 5T2C; -; . ProteinModelPortal P08865; -; . SMR P08865; -; . BioGrid 110115; 218; . DIP DIP-32878N; -; . IntAct P08865; 42; . MINT MINT-1402850; -; . STRING 9606.ENSP00000346067; -; . ChEMBL CHEMBL6119; -; . DrugBank DB04985; PCK3145; . iPTMnet P08865; -; . PhosphoSitePlus P08865; -; . SwissPalm P08865; -; . BioMuta RPSA; -; . DMDM 125969; -; . EPD P08865; -; . MaxQB P08865; -; . PaxDb P08865; -; . PeptideAtlas P08865; -; . PRIDE P08865; -; . TopDownProteomics P08865; -; . DNASU 3921; -; . Ensembl ENST00000301821; ENSP00000346067; ENSG00000168028; . GeneID 3921; -; . KEGG hsa:3921; -; . UCSC uc003cjp.4; human; . CTD 3921; -; . DisGeNET 3921; -; . GeneCards RPSA; -; . HGNC HGNC:6502; RPSA; . HPA CAB009561; -; . MalaCards RPSA; -; . MIM 150370; gene; . MIM 271400; phenotype; . neXtProt NX_P08865; -; . OpenTargets ENSG00000168028; -; . Orphanet 101351; Familial isolated congenital asplenia; . PharmGKB PA30287; -; . eggNOG KOG0830; Eukaryota; . eggNOG COG0052; LUCA; . GeneTree ENSGT00390000015036; -; . HOVERGEN HBG054466; -; . InParanoid P08865; -; . KO K02998; -; . PhylomeDB P08865; -; . TreeFam TF300100; -; . Reactome R-HSA-156827; L13a-mediated translational silencing of Ceruloplasmin expression; . Reactome R-HSA-156902; Peptide chain elongation; . Reactome R-HSA-1799339; SRP-dependent cotranslational protein targeting to membrane; . Reactome R-HSA-192823; Viral mRNA Translation; . Reactome R-HSA-2408557; Selenocysteine synthesis; . Reactome R-HSA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol; . Reactome R-HSA-72649; Translation initiation complex formation; . Reactome R-HSA-72689; Formation of a pool of free 40S subunits; . Reactome R-HSA-72695; Formation of the ternary complex; and subsequently; the 43S complex Reactome R-HSA-72702; Ribosomal scanning and start codon recognition; . Reactome R-HSA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit; . Reactome R-HSA-72764; Eukaryotic Translation Termination; . Reactome R-HSA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); . Reactome R-HSA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); . ChiTaRS RPSA; human; . EvolutionaryTrace P08865; -; . GeneWiki Ribosomal_protein_SA; -; . GenomeRNAi 3921; -; . PRO PR:P08865; -; . Proteomes UP000005640; Chromosome 3; . Bgee ENSG00000168028; -; . ExpressionAtlas P08865; baseline and differential; . Genevisible P08865; HS; . GO GO:0030686; C:90S preribosome; IBA:GO_Central; . GO GO:0005737; C:cytoplasm; IDA:UniProtKB; . GO GO:0005829; C:cytosol; TAS:Reactome; . GO GO:0022627; C:cytosolic small ribosomal subunit; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0016020; C:membrane; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0005634; C:nucleus; TAS:UniProtKB; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0005055; F:laminin receptor activity; IEA:InterPro; . GO GO:0043022; F:ribosome binding; IPI:UniProtKB; . GO GO:0003723; F:RNA binding; IDA:UniProtKB; . GO GO:0003735; F:structural constituent of ribosome; IBA:GO_Central; . GO GO:0001618; F:virus receptor activity; IEA:UniProtKB-KW; . GO GO:0007155; P:cell adhesion; NAS:ProtInc; . GO GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA; 5.8S rRNA; LSU-rRNA) IBA:GO_Central . GO GO:0000461; P:endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA; 5.8S rRNA; LSU-rRNA) IBA:GO_Central . GO GO:0000184; P:nuclear-transcribed mRNA catabolic process; nonsense-mediated decay; TAS:Reactome GO GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central; . GO GO:0006407; P:rRNA export from nucleus; IBA:GO_Central; . GO GO:0006364; P:rRNA processing; TAS:Reactome; . GO GO:0006614; P:SRP-dependent cotranslational protein targeting to membrane; TAS:Reactome; . GO GO:0006412; P:translation; IC:UniProtKB; . GO GO:0006413; P:translational initiation; TAS:Reactome; . GO GO:0019083; P:viral transcription; TAS:Reactome; . CDD cd01425; RPS2; 1; . HAMAP MF_03015; Ribosomal_S2_euk; 1; . HAMAP MF_03016; Ribosomal_S2_laminin_receptor; 1; . InterPro IPR027504; 40S_ribosomal_SA; . InterPro IPR032281; 40S_SA_C; . InterPro IPR001865; Ribosomal_S2; . InterPro IPR018130; Ribosomal_S2_CS; . InterPro IPR027498; Ribosomal_S2_euk; . InterPro IPR005707; Ribosomal_S2_euk/arc; . InterPro IPR023591; Ribosomal_S2_flav_dom; . PANTHER PTHR11489; PTHR11489; 1; . Pfam PF16122; 40S_SA_C; 1; . Pfam PF00318; Ribosomal_S2; 2; . PRINTS PR00395; RIBOSOMALS2; . SUPFAM SSF52313; SSF52313; 1; . TIGRFAMs TIGR01012; uS2_euk_arch; 1; . PROSITE PS00962; RIBOSOMAL_S2_1; 1; . PROSITE PS00963; RIBOSOMAL_S2_2; 1; .

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